Email: emmanuelchidebe@delsu.edu.ng

  • Area of Specialization: Neuropharmacology
  • Department of Pharmacology

  • Mr. Chidebe E.O. is a dedicated academic and researcher in the Department of Pharmacology. He holds a Master of Science (M.Sc.) degree from the University of Ibadan, Nigeria. His primary research interest is in neuropharmacology, with a focus on the pharmacological mechanisms underlying nervous system function and dysfunction. In addition to neuropharmacology, Mr. Chidebe is actively involved in research on immunopharmacology, aging, and nutrition. These interests align with his broader goal of advancing the understanding of disease mechanisms and improving therapeutic strategies, through multidisciplinary techniques, and the promotion of evidence-based approaches to healthcare and wellness.
    My Publications
  1. Ben-Azua, B., Asiwe, J.N., Oritsemuelebi, B., Chidebe, E.O., Onuelua, J.E., Isibor, H., Ogheneoruese, O., Demaki, W.E., Otuachaa, S.O. and Omogbiya, A.I. (2025) Morin inhibits oxidative stress and inflammation in the cardiorenal system associated with post-traumatic stress and alcohol use disorders in mice. , Clinical Traditional Medicine and Pharmacology/Elsevier
    https://www.sciencedirect.com/science/article/pii/S2097382925000046 Vol.6 Pages: 200196

  2. Efejene, O.I., Igabari, J.N., Orororo, O.C., Chidebe, E.O., Aisuodionoe, E.M., Osirim, E., Deloache, S., Ofiebor, L., Bassey, E.G. and Iweriebor, O.B. (2025) Factors Influencing Women's Attitudes towards Family Planning: An Explorative Study in Eku Community, Delta State, Nigeria., Asian Journal of Advanced Research and Reports
    https://hal.science/hal-05104658/ Vol.31(19) Pages: 6

  3. Chidebe, E.O., Ben-Azu, B., Oritsemuelebi, B., Moke, E.G., Omogbiya, I.A. and Theresa, E. (2025) Diosgenin mitigates oxidative stress and inflammation within the hepatorenal system associated with epilepsy and alcohol use disorders in murine models, Phytomedicine Plus/Elsevier
    https://www.sciencedirect.com/science/article/pii/S2667031325001046 Vol. Pages: 100833

  4. Chidebe, E.O., Moke, E.G., Asiwe, J.N., Ben-Azu, B., Demaki, W.E., Oritsemuelebi, B., Arighwrode, O., Avabore, A.N., Omogbiya, A.I., Eduviere, A.T. and Umukoro, E.K. (2024) Therapeutic effect of coenzyme-Q10 pretreatment on isoprenaline-induced cardiogenic hepatorenal complications in rats, International Journal of Physiology, Pathophysiology and Pharmacology/e-Century Publishing Corporation
    https://pmc.ncbi.nlm.nih.gov/articles/PMC11751547/ Vol.16(6) Pages: 126

  5. Adebayo, O.G., Ben-Azu, B., Akpofure, E., Modo, E.U., Ndidiamaka, I.P., Enya, J.I., Udoeyop, F.A., Oritsemuelebi, B., Chidebe, E.O., Chimezie, J. and Omeiza, N.A. (2024) Zingiber officinale Roscoe extract improves nigrostriatal dopaminergic activity in rotenone-induced Parkinsonian mice: Implication of COX-2/TNF-a/IL-6 and antioxidant enzyme crosstalk in the immunoinflammatory responses., Phytomedicine Plus/Elsevier
    https://www.sciencedirect.com/science/article/pii/S266703132400085X Vol.4(4) Pages: 100610

  6. Umukoro, E.K., Elijah, O.B., Igben, V.O., Chidebe, E.O. and Moke, E.G. (2024) Making the Case for Development of Forensic Science in a Developing Country with Emphasis on Forensic Pharmacology: The Nigerian Perspective. , Journal of Applied Sciences and Environmental Management
    https://www.ajol.info/index.php/jasem/article/view/273175 Vol.28(7) Pages: 2095-2104

  7. Ben-Azu, B., Adebayo, O.G., Fokoua, A.R., Oritsemuelebi, B., Chidebe, E.O., Nwogueze, C.B., Kumanwee, L., Uyere, G.S.E. and Emuakpeje, M.T. (2024) Antipsychotic effect of diosgenin in ketamine-induced murine model of schizophrenia: Involvement of oxidative stress and cholinergic transmission, IBRO Neuroscience Reports/Elsevier
    https://www.sciencedirect.com/science/article/pii/S2667242123022960 Vol.16 Pages: 86-97

  8. Asiwe, J.N., Moke, E.G., Ben-Azu, B., Onuelu, J.E., Nwabuoku, U.S., Anachuna, K.K., Demaki, W.E., Chidebe, E.O. and Oritsemuelebi, B. (2024) Hepato-renal oxidative disturbances following acute ß-adrenergic stimulation by isoprenaline in male Wistar rat: Attenuative role of taurine, a ß-amino acid, Nutrire/Springer International Publishing
    https://link.springer.com/article/10.1186/s41110-024-00267-6 Vol.49(1) Pages: 25

  9. Ben-Azu, B., Chidebe, E.O., Toloyai, P.E.Y., Annafi, O.S., Oritsemuelebi, B., Asiwe, J., Moke, G.E., Ajayi, A.M., Chukwuebuka, N.B., Onuelu, J.E. and Utomi, C.W. (2024) Adaptogenic action of diosgenin againsts chronic unpredictable mild stress-induced neuroimmune dysfunction of HPA axis reverses psychiatric behavior in mice, Clinical Traditional Medicine and Pharmacology/Elsevier
    https://www.sciencedirect.com/science/article/pii/S2097382924000192 Vol.5(2) Pages: 200148

  10. Moke, E.G., Asiwe, J.N., Ben-Azu, B., Chidebe, E.O., Demaki, W.E., Umukoro, E.K., Oritsemuelebi, B., Daubry, T.M., Nwogueze, B.C., Ahama, E.E. and Erhirhie, E.O. (2024) Co-enzyme-Q10 and taurine abate isoprenaline-mediated hepatorenal dysregulations and oxidative stress in rats, Clinical Nutrition Open Science/Elsevier
    https://www.sciencedirect.com/science/article/pii/S2667268524000664 Vol.57 Pages: 10-25

  11. Moke, E.G., Edje, E.K., Daubry, T.M., Nwogueze, B.C., Ataikiru, O.M., Umukoro, E.K., Omorodion, I.L., Chidebe, E.O., Demaki, W.E., Aluya, S.O. and Osayande, J. (2024) Phytopharmacological Activities of Spondias mombinLinn: A Review, Tropical Journal of Phytochemistry and Pharmaceutical Sciences
    http://www. doi. org/10.26538/tjpps/v3i1. 1. Vol.3(1) Pages: 117-123

  12. Ben-Azu, B., Adebayo, O.G., Moke, E.G., Omogbiya, A.I., Oritsemuelebi, B., Chidebe, E.O., Umukoro, E., Nwangwa, E.K., Etijoro, E., Umukoro, E. and Mamudu, E.J. (2023) Geraniol attenuates behavioral and neurochemical impairments by inhibitions of HPA-axis and oxido-inflammatory perturbations in mice exposed to post-traumatic stress disorder. , Journal of Psychiatric Research/Elsevier Ltd
    https://www.sciencedirect.com/science/article/abs/pii/S0022395623005022 Vol.168 Pages: 165-175

  13. Ajayi, A.M., John, K.A., Emmanuel, I.B., Chidebe, E.O. and Adedapo, A.D., (2021) High-fat diet-induced memory impairment and anxiety-like behavior in rats attenuated by peel extract of Ananas comosus fruit via atheroprotective, antioxidant and anti-inflammatory actions, Metabolism open/Elsevier B.V.
    https://www.sciencedirect.com/science/article/pii/S2589936821000013 Vol.9 Pages: 100077

  14. Ajayi, A. M., Chidebe, E. O., Ben-Azu, B., & Umukoro, S. (2020) Chrysophyllum albidum (African star apple) fruit-supplemented diet enhances cognitive functions and attenuates lipopolysaccharide-induced memory impairment, oxidative stress, and release of proinflammatory cytokines, Nutrire/Springer International Publishing
    https://link.springer.com/article/10.1186/s41110-020-00123-3 Vol.45 Pages: 1-13