Email: ocorororo@delsu.edu.ng
- Area of Specialization: TOXICOLOGY
- Department of Medical Biochemistry
- I am a native of Eku, in Agbon Clan, Ethiope East Local Government Area of Delta State, where I had my Primary and Secondary Education.
A display of academic and moral excellence was also the case when I entered DELSU in 2005 to read Biochemistry. I graduated in 2009 as the best graduating student in the Department. I obtained a Ph.D from the Department of Biochemistry, Faculty of Science, Delta State University, Abraka in 2019 under the tutelage of Professor S. O. Asagba and Professor N. J. Tonukari.
I also hold three other Certificates/degrees which have had profound positive effects on my work as a teacher and researcher. First is a Certificate in Management from the Nigerian Institute of Management (NIM), 2011, which taught me vast managerial skills that I have applied proficiently in classroom Management. Second is a Post Graduate Diploma in Education, obtained in 2014 from the Institute of Education, Faculty of Education, Delta State University, Abraka. Thirdly, I hold a Masters of Divinity (M.Div) in Theology from the Prestigious Baptist Theological Seminary, Eku where I was armed with requisite competences in spiritual formation, theology, philosophy, leadership and management skills, which are paramount in the development of the complete person.
Basically, my research is in two main domains of Biochemistry: Toxicology and Biotechnology and that is as a result of the training I received from my academic fathers – Prof. S. O. Asagba and Prof. N. J. Tonukari.
I am a member of the Nigerian Society of Biochemistry and Molecular Biology, Member Nigerian Environmental Society, Graduate Member of the Nigerian Institute of Management and a Registered Teacher with the Teachers Registration Council of Nigeria.
My Publications- Ugbome, A. O., Orororo, O. C., Efejene, O. I., Busari, A. A., Badmos, K., Obadiah, C. C., Akinshipo W. A., Awhin, E. P., Odeghe, O. B., Okoro, E. O. and Egbune, E. O. (2025) Effects of Black Seed (Nigella sativa) oil on Hepatic Function Parameters in Rats Induced with Diabetes Mellitus and Periodontitis, Nigerian Journal of Biochemistry and Molecular Biology
Vol.39(3): Pages: 161-169.
- Enaohwo, M. T., Orororo, O. C., Basil-Iwhiwhu, O. P., Jaiyeoba-ojigho, J. E., Dunkwu, C. C., Enyi, K. C. and Mode, J. (2025) Effects of Justicia carnea leaf extract on cerebral oxidative stress parameters and expression of cellular adhesion molecule-1 in albino mice exposed to TNBS., The Journal of Basic and Applied Zoology
https://doi.org/10.1186/s41936-025-00445-6 Vol.86:26 Pages: 161-169.
- Denedo, A. R., Rotu, A. R. and Orororo, O. C. (2025) Biochemical Assessment of Oxidative Stress in African Catfish (Clarias Heterobronchus) from Oil Polluted Rivers in The Niger Delta, Nigeria., Journal of Research in Zoology
Vol.8 (2): Pages: 39-51.
- Enaohwo, M. T., Orororo, O. C., Jaiyeoba-Ojigho, J. E., Dunkwu, C. C., Enyi, K. C., Oghaimeh, G. O. and Mode, J. (2025) Justicia carnea Extract Mitigates TNBS-Induced Liver Inflammation by Ameliorating Oxidative Stress, Improving Liver Function Indices, and Normalizing NF-?b/Caspase 3 Expression., Tropical Journal of Natural Product Research
https://doi.org/10.26538/tjnpr/v9i4.29 Vol.9(4): Pages: 1574 – 1583
- Busari, A. A., · Efejene, I. O., Olayemi, S. O., Orororo, O. C., and Egbune, E. O. (2024) Evaluation of antibiotic use and analysis of ciprofloxacin and gentamicin residue in fish samples from farms in Lagos, Nigeria, Environmental Monitoring and Assessment
Vol.196:127: Pages: 1-10.
- Efekemo, O., Davies, I. C., and Orororo, O. C. (2024) Water Quality Assessment and Heavy Metal Levels in Mudskipper (Periophthalmus papilio), Sediments and Water of Mangrove Swamps, Rivers State, Nigeria., African Journal of Environment and Natural Science Research
Vol.7(1): Pages: 128-145.
- Olorunfemi, D. I., Oteri, O., Orororo, O. C., Enize, T. B., Pere, C. and Osioma, E. (2024) Genotoxic Effects of Cassava Effluent on the Expression of Selected Genes in the African Catfish, Clarias gariepinus., Journal of Advances in Biology & Biotechnology
Vol.27(5): Pages: 352-364.
- Olorunfemi, D. I., Orororo, O. C., Iloduba, N. E., Osioma, E., Kpomah, N. D. and Osio, O. L. (2024) Evaluation of Genotoxicity by Comet assay in tissues of Clarias gariepinus exposed to cassava Effluent., Asian Journal of Biochemistry, Genetics and Molecular Biology
Vol.16 (7): Pages: 98-108.
- Efekemo, O., Orororo, O. C. and Davies, I. C. (2024) Evaluation of Water Quality and Heavy metal Concentrations in Shrimp (P. Monodon), Sediment and Surrounding Water of the Mangrove Swamps, Rivers State, Nigeria, Scientia Africana
Vol.23 (2): Pages: 251-262
- Orororo, O. C., Efekemo, O., Egbune, E. O., Awhin, E. P., Odeghe, O. B., and Okoro, E. O. (2024) Amelioration of Cadmium toxicity in the liver and kidney of Wistar rats by combined Citrus sinensis and Manihot esculenta Leaf extract., International Journal of Biochemistry Research and Review
Vol.23 (6): Pages: 71-79
- Orororo, O. C., Efekemo, O., Odeghe, O. B., Clark, P. D., Awhin, E. P., Egbune, E. O., and Efejene, I. O. (2024) Phytochemical Screening, in vitro antoxidant capacity and Nephro-protective effects of combined extract of Psidium guajava and Carica papaya leaves in rats intoxicated with cadmium, Asian Journal of Medicine and Health
Vol.22 (8): Pages: 86-97.
- Egbune, E.O. Egbune, O. U., Ezedom, E., Dennis-Eboh, U., Orororo, O.C., Tonukari, N.J. (2024) Enhancement of Biochemical Parameters and enzyme activity in solid-state fermented and biofortified maize cobs utilizing yeasts and plant extracts, Bioresource Technology
Vol.26, 101874. Pages: 101874.
- Idenyi, O. M., Orororo, O. C., Efejene, I. O., Aisuodionoe, M. E. and Umoren, U. F (2024) Evaluation of Anti-Inflammatory and Analgesic Effects of Allophylus spicatus Lead Extract in Mice., Journal of Complementary and Alternative Medical Research
Vol.25 (9): Pages: 59-68.
- Busari, A. A., Obadiah, C. C., Orororo, O. C., Efejene, I. O., Aisuodionoe, M. E., Osirim, E., DeLoache, S., Ebu, C. I., Adejare, A. A. and Badmos K. (2024) Assessment of Cardiovascular Function in Periodontitis and Diabetes Mellitus Induced Rats Treated with Black Seed (Nigella sativa) Oil., Asian Journal of Cardiology Research
Vol.7(1): Pages: 230-244.
- Onobrudu, D. A., Nzebude, C. P. and Orororo, O. C. (2024) Comparative Analysis of the Phytochemicals, Minerals, Antioxidant and Antimicrobial Activities of Aqueous and Ethanolic Extracts of Rauvolfia vomtoria Leafs, Asian Plant Research Journal
Vol.12(5): Pages: 67-81.
- Odeghe, O. B., Orororo, O.C., Agboola, O.E., Onyeso, G., Dennis-Eboh, U., Ekakitie, L.I., Awhin, E. P. and Ojugbeli, E.T. (2024) Phytochemical Profiling and In vitro Antioxidant Activity of Methanolic Extracts from Fadogia cienkowskii Leaves, Asian Plant Research Journal
Vol.12 (6): Pages: 110-120.
- Orororo, O.C. and Asagba, S. O. (2024) Effects of Hibiscus sabdariffa L. Anthocyanins on Body Weight, Lipid Peroxidation, and Lipid Profile of Cadmium-exposed Rats., Saudi Journal of Forensic Medical Sciences
Vol.4: Pages: 21-25.
- Olorunfemi, D. I., Gabriela-Mary, O. N., Olumide, A., Ebisintei, P., Okunoja, H. B., Orororo, O.C., Kpomah, E. D. and Tesi, J. N. (2024) biochemical, histological and molecular investigation of fish exposed to a brewery effluent, Journal of Basic and Applied Zoology
Vol.85: 64: Pages: 1-12.
- Aganbi, E., Odeghe, O. B., Orororo, O. C., Ojugbeli, E.T. and Mordi, J. C. (2024) Fermented Ofada rice (A Nigerian recipe) attenuates renal and hepatic dysfunction induced by crude oil poisoning in Wistar Rats. , Babcock University Medical Journal
Vol.7(2): Pages: 14-24.
- Orororo, O. C. and Udi, O. A. (2023) Assessment of the hepato-protective effects of combined ethanolic extract of Psidium guajava and Carica papaya leafs in rats challenged with Cadmium, Nigerian Journal of Pure and Applied Sciences;
Vol.36: Pages: 4521-4530.
- Kpomah, E. D. and Orororo, O. C. (2023) Evaluation of Some Heavy Metals in Selected Canned Sardine Sold in Yenagoa Metropolis, Bayelsa State, Southern Nigeria, Nigerian Journal of Science and Environment
Vol.21(1): Pages: 224 – 236.
- Egbune, O. U., Egbune, E. O., Orororo, O. C., Ezedom, T., · Onojakpor, O., Sabo, A. M. and · Amadi, K. (2023) Chronic cassava meal modulates body weight, histology and weight of reproductive organs in male albino rats., Toxicology and Environmental Health Sciences
https://doi.org/10.1007/s13530-023-00179-4 Vol.21(1): Pages: 224 – 236.
- Aganbi, E; Egbune, E. O; Orororo, O. C; Ezedom, T; Egbune, O. U, Tonukari, N. J. (2023) Effect of microbial cell-size on solid state fermentation of Cowpea (Vigna unguiculata L. Walp) and Groundnut (Arachis hypogaea L.) by Rhizopus oligosporus, J. Appl. Sci. Environ. Manage.
Vol.27 (6): Pages: 1093-1103.
- Eghaghaa, E.P., Egbune, E.O., Ezedom, T., Orororo, O. C., Anigboro, A.A. and Tonukari, N.J. (2023) Biochemical Assessment of Solid-State Fermented Elephant Grass and its Potential Incorporation in Broiler's Diets, Nig. J. Biotech.;
Vol.40(1): Pages: 29-42.
- Egbune, E. O., Ezedom, T., Orororo, O. C., Egbune, O. U., Avwioroko, O. J., Aganbi, E., Anigboro, A. A., and Tonukari, N. J. (2023) Solid-state fermentation of cassava (Manihot esculenta Crantz): a review. , World Journal of Microbiology and Biotechnology
Vol.39:259; Pages: 1-20
- Orororo, O. C., Mordi, J. C., Opute, U. A., Efejene, I. O., Egbune, E. O., Busari, A. A., Badmos, K., Obadiah, C. C. and Akinshipo, W. A. (2023) Black Seed Oil-induced Amelioration of Renal Dysfunction in a Rat Model of Diabetes Mellitus and Periodontitis., Trop J Nat Prod Res
Vol.7(7): Pages: 3524-3531.
- Efejene, I. O., Orororo, O. C., Odeghe, O, B. and Efetoboh, E. (2023) Effect of Ethanolic Extract of Zingiber Officinale Rhizome on Blood Glucose Level in Glucose-induced Hyperglycaemic Wistar Rats, African Scientist
Vol.24(2): Pages: 263-269.
- 32) Odeghe, O. B., Opajobi, A.O., Ajala, M. O. and Orororo, C. O. (2023) Enzyme inhibitory properties, free radical scavenging activity and phytochemical profile of Vitex simplicifolia leaf, Eur. Chem. Bull.
Vol.12(8): Pages: 8666-8682
- Odeghe OB, Orororo CO, Egbune EO, Onobrudu DA, Nwiloh BI and Bassey UE. (2023) Phytochemical analysis, antioxidant capability, and inhibition studies of the aqueous extract of Phyllanthus discoideus root., Biomed Biotechnol Res J
Vol.2023;7: Pages: 411-9.
- Ohwode, J. O., Egbune, E. O., Dennis-Eboh, U., Ezedom, T., Orororo, O. C., Anigboro, A. A., Tonukari, N. J. (2023) Biochemical Evaluation of Pre-treated Unpeeled Cassava Roots (Manihot esculenta Crantz) and its application in Alcohol Production, Nigerian Journal of Science and Environment
Vol.21 (2) Pages: 514 – 542.
- Egbune, E. O., Orororo O. C., Ezedom, T., Egbune. O. U., Ebuloku, C. S., Orogun, J. B., Bamiyor, R. A., Ayigwe, G. E., Bialoseh, F. O., Edike, O. V., Daudu, E. l., Edewor, F. A. and Tonukari, N. J. (2023) Production of L-lysine by Corynebacterium glutamicum using aqueous leaf extracts of tropical grasses as substrate , Food and Humanity
Vol.2023 Pages: 1592–1597.
- Egbune, E. O., Avwioroko, O. J., Orororo, O. C., Egbune, O. U., Aganbi, E., Anigboro, A. A. and Tonukari, N. J. (2023) Rhizopus oligosporus alkaline protease in cassava fermentation: Characterization and detergent potential, Biocatalysis and Agricultural Biotechnology
Vol. 54 (2023) Pages: 102954
- Egbune, E. O., Ezedom, T., Odeghe, O. B., Orororo, O. C., ·Egbune, O. U., Ehwarieme, A. D., Aganbi, E., Ebuloku, C. S., Chukwuegbo, A. O., Bogard, E., Ayomanor, E., Chisom, P. A., Edafetano, F. L., Destiny, A and Alebe, P. A., Aruwei, T., Anigboro, A. A. and Tonukari, N. J. (2023) Solid-state fermentation production of L-lysine by Corynebacterium glutamicum (ATCC 13032) using agricultural by-products as substrate, World Journal of Microbiology and Biotechnology
Vol.40:20; Pages: 1-13
- Busari, A. A., Orororo, O. C., Opute, U. A., Efejene, I. O., Badmos, K., Obadiah, C. C., Akinshipo, W. A.. and Egbune, E. O. (2023) Effects of Black Seed Oil on Oxidative Stress Parameters and Gingival Expression of Inducible Nitric Oxide Synthase in Diabetes and Periodontitis-Induced Rats., African Scientist
Vol.24(3): Pages: 376-386.
- Orororo, O. C., Efekemo, O., Osain, B. P., Dodo, O. E., Ideah, O. A. and Feku, J. D. (2023) Combined Leaf Extract of Vernonia Amygdalina And Occimum Gratissimum Ameliorates Cadmium-induced Nephro-toxicity In Wistar Rats., Asian Pacific Journal of Science and Technology
Vol.28(03): Pages: 1-8.
- Aimuamhosa, O. S., Tonukari, N. J., Avwioroko, O. J. and Orororo, O. C. (2022) Supplemental increase of vegetable oil in pig feed formulated from agro-industrial waste: effects on body weight and biochemical parameters of pigs, African Scientist Journal
Vol.23(4): Pages: 320-325
- Orororo, O. C. and Asagba, S. O. (2022) Response of Oxidative Enzymes to Hibiscus sabdarriffa L. anthocyanins Treatment in Cadmium-exposed Rats. , European Modern Studies Journal;
Vol.6(1): Pages: 257-269
- Orororo, O. C. and Asagba, S. O. (2022) Treatment with Hibiscus sabdarrifa L Anthocyanins Improve Hematological Parameters in Rats Exposed to Cadmium. , Journal of Exploratory Research in Pharmacology
DOI: 10.14218/JERP.2022.00003 Vol.6(1): Pages: 2022
- Efekemo, O. and Orororo O. C. (2022) Effect of mixture of leaf extract of Ocimum gratissimum and Vernonia amygdalina on cadmium induced hepatotoxicity in wistar rats. , Journal of Biochemistry International
Vol.9(4): Pages: 73-81
- Orororo, OC; Efekemo, O; Clark, PD; Ajiri, S; Alao, V; Orumo, B; Eduvie, O. (2022) Assessment of oxidative stress indices in the tissues of cadmium-challenged rats treated with Manihot esculenta and Citrus sinensis combined leaf extract., Journal of Applied Science and Environmental Management
Vol.26 (9): Pages: 1515-1522
- Ekakitie, L. I., Orororo O. C. and Okpoghono, J., (2022) Curative influence of natural honey bee on liver function parameters in aluminium nitrate-induced wistar rats., Nigerian Journal of Biochemistry and Molecular Biology
Vol.37(3): Pages: 175-180
- Orororo, O. C., Efekemo, O. and Udi, O. A (2022) Changes in liver histology, hematological parameters and lipid profile of cadmium-exposed rats treated with combined leaf extract of Vernonia amygdalina and Occimum gratissimum, Asian Journal of Medicine and Health
Vol.20(11): Pages: 195-203
- Orororo, O. C, Asagba, S. O., Egbune, E. O. and Efejene, O. I. (2022) Sperm parameters and histological changes in testes of cadmium-exposed rats treated with Hibiscus sabdarrifa L. anthocyanins, Sokoto Journal of Medical Laboratory Science
Vol.7(3): Pages: 114-122.
- Orororo, O. C. and Asagba, S. O (2022) Cadmium induced hepato-nephro toxicity in rat model: protective and curative influence of Hibiscus sabdarrifa L. anthocyanins, Nigerian Journal of Biochemistry and Molecular Biology
Vol.37(3): Pages: 148-157.
- Orororo, O. C. Ogbotu A. and Asagba, S. O. (2022) Evaluation of the in vitro antioxidant properties of Hibiscus sabdariffa L. anthocyanins, Uniport Journal of Engineering and Scientific Research
Vol.7 (1): Pages: 24-30.
- Ekakitie, L. I., Okpoghono, J., Orororo O. C. and Ekakitie, O. A. (2021) Ameliorative prowess of bee honey in the tissues of rats administered aluminium nitrate, Scientific African
Vol.12 (2021) Pages: e00782:1-9
- Ekakitie, L. I., Orororo O. C. and Okpoghono, J., (2021) Changes in haematological parameters of aluminium-exposed rats treated with natural bee honey., IOSR Journal of Environmental Science, Toxicology and Food Technology
Vol.15(5): Pages: 22-25
- Esiekpe, G. T., George, B. O., Orororo, O. C., Akpede, A. A., Okevwe, G. E., Onotugoma, E. and Oguntola, J. (2020) Monodora myristica seed extracts ameliorate crude oil contaminated diet-induced cardiotoxicity in rats. , Thai Journal of Pharmaceutical Sciences;
Vol.44 (3): Pages: 145-151
- Ekakitie, L., Asagba, S. O., Orororo, O. C. (2019) Changes in Tissue Oxidative Enzymes in Rats exposed to Red Bull Energy Drink and Alcohol, Journal of Applied Science and Environmental Management;
Vol.23 (6): Pages: 1175 – 1179.
- Ekakitie, L., Asagba, S. O., Orororo, O. C. (2019) Combined and Separate Effects of Energy Drink and Alcohol on Body Weight and Aminotranferases in Plasma and Tissues of Wistar Rats., Gashua Journal of Sciences and Humanities
Vol.2(2): Pages: 27-34
- Orororo, O. C., Asagba, S. O, Tonukari, N. J., Okandeji, O. J., and Mbanugo J. J. (2018) Hibiscus sabdarrifa L. Anthocyanins-Induced Changes in Reproductive Hormones of Cadmium-Exposed Rats., International Journal of Scientific and Research Publications
Vol.12(4): Pages: 308-311.
- Orororo, O. C., Asagba, S. O, Tonukari, N. J., Okandeji, O. J., and Mbanugo J. J. (2018) Effects of Hibiscus Sabdarrifa L. Anthocyanins on Cadmium-Induced Oxidative Stress in Wistar Rats. , Journal of Applied Science and Environmental Management
Vol.22 (4): Pages: 465 – 470
- Orororo, O. C., Asagba, S. O, Tonukari, N. J., Okandeji, O. J., and Mbanugo J. J. (2018) Cadmium-Induced Testicular Damage in Wistar Rats: Protective Effects of Hibiscus sabdariffa L. Anthocyanins. , International Journal of Biochemistry Research and Review
Vol.21(4): Pages: 1-8
- Orororo, O. C., Asagba, S. O, Tonukari, N. J., Okandeji, O. J., and Mbanugo J. J. (2018) Comparative Assessment of the Antioxidant Properties of Hibiscus sabdarrifa L Anthocyanins and its Aqueous Extract in Cadmium-exposed Rats, Research Journal of Pharmaceutical, Biological and Chemical Sciences
Vol.9(3): Pages: 836-843
- Orororo O. C., Asagba, S. O., Oghri, E. and Egbune Egoamaka Oliseneku (2017) Comparative Effect Of Garden Egg, Carrot And Oat On Biochemical Parameters In Cadmium Exposed Rats., African Journal of Biochemistry Research
Vol.12(3): Pages: 28-34
- Tonukari, N. J. Egbune E. Oliseneku, Oghenetega J, Avwioroko, Osuvwe C. Orororo, Akpovwehwee A. Anigboro (2016) A Novel Pig Feed Formulation containing Aspergillus niger CSA35 pretreated cassava peels and its effect on growth and selected biochemical parameters of pigs, African Journal of Biotechnology
Vol.15(9): Pages: 776-785.
- Orororo O. C., Tonukari, N. J., Avwioroko, O. J. and Ezedom, T. (2014) Effect of Supplementation of Animal Feed with Dried Cassava (Manihot esculenta) Peels, and Stems of Vernonia amygdalina and Pennisetum purpereum on Some Biochemical Parameters in Pigs. , Nigerian Society for Experimental Biology (NISEB) Journal
Vol.14(4): Pages: 177-183