Dr. MODO, Emmanuel Uchechukwu (SENIOR LECTURER)

Email: emmanuelmodo@delsu.edu.ng

• Area of Specialization: Environmental Toxicology
• Department of Biochemistry
My Publications
• Johnson, J. T. & Modo, E. U. (2024) Effect of Liv.52hb, Ganoderma Lucidum, Stc30, and Astaxanthin on Serum TNF-a And Liver Function Indices Following CCL4 Induced Hepatocellular Carcinoma in Albino Wistar Rats Model, International Journal of Research in Medical and Clinical Science
  https://www.researchgate.net/publication/378691390_Effect_of_Liv52hb_Ganoderma_Lucidum_StC30_and_Astaxanthin_on_Serum_TNF-a_And_Liver_Function_Indices_Following_CCL4_Induced_Hepatocellular_Carcinoma_in_Albino_Wistar_Rats_Model Vol.2 (1) Pages: 25-36
  
  
• Elizabeth Umoren, Jerome Ndudi Asiwe, Idara Asuquo Okon, Albert, Levi Amangieka, Clement U. Nyenke, Anthony Chibuzor Nnamudi, Emmanuel U. Modo, Augustine I. L. Bassey, Gospel Nwikue & Okon E. Etim (2023) Terminalia catappa attenuates phenylhydrazine-induced anaemia and hepato-renal toxicity in male Wistar rat by boosting blood cells, modulation of lipoproteins and up-regulation of in vivo antioxidant armouries, Biomarkers
  https://www.tandfonline.com/doi/full/10.1080/1354750X.2023.2166588 Vol.28 (3) Pages: 302-312
  
  
• Elizabeth B. Umoren, Idara A. Okon, Emmanuel U. Modo, Okon E. Etim, Providence I. Brown, Daniel U. Owu, Augustine I.L. Bassey (2023) Jatropha tanjorensis Euphorbiaceae ameliorates aspirin-induced hepatotoxicity and maintain electrolytes balance in albino Wistar rats, Phytomedicine Plus
  https://www.sciencedirect.com/science/article/pii/S2667031323000465 Vol.3(2) Pages: 100450 (1-8)
  
  
• Olusegun G. Adebayo, Cletus Ikechukwu Otene, Modo U. Emmanuel, Favour C. Onwuka, Wadioni Aduema, Benneth Ben-Azu, Gospel Nwikue, Jerome Ndudi. Asiwe, Amalachukwu Okwukwe Ike, Iheanyichukwu Wopara, Noah A. Omeiza, Jude Ijuo Abeje, Samuel A. Onasanwo (2023) Chronic intermittent oxygen deprivation alters hippocampal cholinergic and glutamatergic system via oxido-inflammatory burden and HIF-1a/Bcl-2 activity in hypothyroid mice: Ameliorative role of Ginkgo biloba supplement, Phytomedicine Plus
  https://www.sciencedirect.com/science/article/pii/S2667031323000477 Vol.3(2) Pages: 100451 (1-8)
  
  
• E. B. Umoren, I. A. Okon, C. Nyenke, E. Modo, N. Amadi and P. I. Brown (2023) Jatropha tanjorensis Euphorbiaceae Ethanolic Leaves Extract Reverses Phenylhydrazine Induced Haematological Alterations in Albino Wistar Rats, European Journal of Nutrition & Food Safety
  http://publish.journalgazett.co.in/id/eprint/1220/1/Umoren1552023EJNFS98624.pdf Vol.15 (5) Pages: 20-29
  
  
• Olusegun G. Adebayo, Benneth Ben-Azu, Egwonor Akpofure, Modo U. Emmanuel, Iheanyichukwu Wopara, Wadioni Aduema, Lawrence Dayo Adedayo, Jude Ijuo Abeje (2023). (2023) Zingiber officinale (Ginger) Methanol Extract Abates Kidney Dysfunction in Mice Co-exposed to Sub-chronic Alcohol Intoxication and Post-traumatic Stress Disorder, Clinical Complementary Medicine and Pharmacology
  https://www.sciencedirect.com/science/article/pii/S2772371223000384 Vol.3 Pages: 100116 (1-12)
  
  
• Olusegun G. Adebayo, Wadioni Aduema, Modo U. Emmanuel, Benneth Ben-Azu, Blessing O. Orji, Ekam Akpakpan, Oluwakemi Rachael Adebayo, Ogechukwu G. Onuoha, Abayomi M. Ajayi (2022) The Anti-Parkinson Potential of Gingko biloba-Supplement Mitigates Cortico-Cerebellar Degeneration and Neuropathobiological Alterations via Inflammatory and Apoptotic Mediators in Mice, Neurochemical Research
  https://link.springer.com/article/10.1007/s11064-022-03600-5 Vol. 47 Pages: 2211-2229
  
  
• Ifenna Ilechukwu, Ben Enoluomen Ehigiator, Inemesit Okon Ben, Chinedu Joseph Okonkwo, Oluwakemi S. Olorunfemi, Uchechukwu Emmanuel Modo, Chibuamam Ezinwanneamaka Ilechukwu, Ngozika Juliet Ohagwa (2022) Chronic toxic effects of polystyrene microplastics on reproductive parameters of male rats, Environmental Analysis Health and Toxicology
  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9314200/pdf/eaht-37-2-e2022015.pdf Vol. 37(2) Pages: 1-8
  
  
• Emmanuel Uchechukwu Modo, Ijeoma Nina Eke, Utibe Evans Bassey, Anthony Chibuzor Nnamudi, Ekam Ime Akpakpan, Okon Effiom Etim, Iheanyichukwu Wopara, Prosper Great Legborsi (2022) Up-regulation of oxidative stress and inflammation in the brain of albino wistar rats following sub-acute administration of Synclisia scabrida root extract , TMR Integrative Medicine
  https://www.tmrjournals.com/public/articlePDF/20221223/6c42860ecd3c49f8b23d51654031323e.pdf Vol.6: Pages: 1-7
  
  
• Iheanyichukwu Wopara, Emmanuel U Modo, Samuel Kelechi Mobisson, G Adebayo Olusegun, EB Umoren, Blessing O Orji, Philippe E Mounmbegna, Stephanie Okoye Ujunwa. (2021) Synthetic Food dyes cause testicular damage via up-regulation of pro- inflammatory cytokines and down-regulation of FSH-R and TESK-1 gene expression, JBRA Assisted Reproduction
  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8312291/ Vol.25(3) Pages: 341–348
  
  
• Iheanyichukwu Wopara, Emmanuel U. Modo, Olusegun G. Adebayo, Samuel K. Mobisson, Jovita O. Nwigwe, Prince I. Ogbu, Vincent U. Nwankwo, Constance U. Ejeawa (2021) Anxiogenic and memory impairment effect of food color exposure: upregulation of oxido-neuroinflammatory markers and acetyl-cholinestrase activity in the prefrontal cortex and hippocampus., Heliyon
  https://www.cell.com/action/showPdf?pii=S2405-8440%2821%2900483-7 Vol. 7 (3) Pages: 1-7
  
  
• ORJI Blessing O., MODO Emmanuel U., OBI Frederick O. (2021) Post-treatment with Hibiscus Sabdariffa Linn calyx extract enhances liver function following chronic paracetamol exposure in mice , Journal of Phytomedicine and Therapeutics
  file:///C:/Users/hp%20pc/Downloads/ajol-file-journals_342_articles_238204_submission_proof_238204-4081-574722-1-10-20221211-1.pdf Vol.20(2) Pages: 656– 669
  
  
• Blessing O. Orji, Frederick O. Obi, Emmanuel U. Modo, Martin Osibemhe and Catherine A. Otitolaiye (2020) Amelioration of paracetamol-induced nephrotoxicity in mice by aqueous extract from the calyx of Hibiscus sabdariffa Linn., Biokemistri
  https://www.researchgate.net/publication/344157500_Amelioration_of_paracetamol-induced_nephrotoxicity_in_mice_by_aqueous_extract_from_the_calyx_of_Hibiscus_sabdariffa#fullTextFileContent Vol.32(1) Pages: 23-34
  
  
• Wopara Iheanyichukwu, Adebayo O. Adegoke , Olusegun G. Adebayo, Modo Emmanuel U., Aziemeola Pius Egelege , Jeremiah T. Gona & Fortune M. Orluwene (2020) Combine colorants of tartrazine and erythrosine induce kidney injury: involvement of TNF-a gene,caspase-9 and KIM-1 gene expression and kidney functions indices, Toxicology Mechanisms and Methods
  https://www.tandfonline.com/doi/pdf/10.1080/15376516.2020.1828523 Vol.31 (1) Pages: 67-72
  
  
• Ajayi, EIO, Modo EU, Kiakubu OT, Molehin OR (2019) Diabetes Care and Wound Healing using Nauclea latifolia, Manihot esculenta, and other natural products. In: Bioactive Food as Dietary Interventions for Diabetes, Eds Ronald Watson and Victor Preedy (United States: Academic Press)
  https://www.sciencedirect.com/science/article/abs/pii/B9780128138229000357 Vol.35 (2) Pages: 545-558
  
  
• Iheanyichukwu Wopara, Augustine A. Uwakwe, Matthew O. Wegwu, Emmanuel U. Modo, Samuel C. Anyalenkeya (2019) Effect of Ethanolic Root Extract of Sphenocentrum jollyanum, Baphia nitida, Pinus koraiensis, and Sildenafil on Some Haematological Test Parameters in Albino Wistar Rats, International Journal of Research and Scientific Innovation (IJRSI)
  https://www.rsisinternational.org/journals/ijrsi/digital-library/volume-6-issue-3/44-48.pdf Vol.6(3) Pages: 44-48
  
  
• Wopara, Iheanyichukwu, Modo Emmanuel U. & Mounmbegna Philippe, E. (2019) The effect of Xylopia aethiopica on the Urea and Creatinine levels of male albino wistar rats, Imperial Journal of Interdisciplinary Research
  https://www.researchgate.net/publication/333338211_The_effect_of_Xylopia_aethiopica_on_the_Urea_and_Creatinine_levels_of_male_albino_wistar_rats Vol.5 (3) Pages: 52-55
  
  
• Okpogba AN, Amah AK, Ogbodo EC, Ujowundu FN, Odeghe OB, Analike RA, Amah UK, Oguaka VN, Wopara I, Modo EU. (2019) Assessment of lipid profile levels of chickens (Gallus gallus domestica) exposed to factory sites in Nnewi, Anambra State, South Eastern Nigeria, Journal of Diagnostic Pathology and Oncology
  https://www.jdpo.org/journal-article-file/9043 Vol.4 (2) Pages: 107-109
  
  
• A.N. Okpogba, E.C. Ogbodo, M.N. Izuogu, A. K. Amah, D.C. Ejiofor, I. Wopara, F.N. Ujowundu, C. Nwanegwo, E.U. Modo, C.N. Chinaka (2019). (2019) Assessment of histopathological effect of factory effluents on the liver and kidney tissues of chickens (Gallus gallus domestica) reared around factory sites in Nnewi Metropolis, Anambra State, Nigeria., Panacea Journal of Medical Sciences
  https://www.ipinnovative.com/journals/PJMS/article-details/9171/volume/272/issue/714 Vol. 9 (1) Pages: 3-6
  
  
• Wopara Iheanyichukwu, Mounmbegna P. P. E, Ike Amanda and Modo Emmanuel U. (2019) Hepatotoxic Effect of Tartrazine and Erythrosine on Male Wistar Rats. , EUROPEAN JOURNAL OF PHARMACEUTICAL AND MEDICAL RESEARCH (ejpmr)
  https://journals.indexcopernicus.com/api/file/viewByFileId/753790.pdf Vol. 6 (7) Pages: 107-110
  
  
• A.N. Okpogba, E.C. Ogbodo, O.B.Odeghe, E.U. Modo, I. Wopara, R.A Analike,F.N. Ujowundu, V.N. Oguaka, A. K. Amah, J.C. Okpogba (2019) (2019) Assessment of liver function status of chickens (Gallus gallus domestica) exposed to factory sites in Nnewi, Anambra State, South Eastern Nigeria, International Journal of Forensic Medicine and Toxicological Sciences
  https://www.researchgate.net/publication/334467131_Assessment_of_liver_function_status_of_chickens_Gallus_gallus_domestica_exposed_to_factory_sites_in_Nnewi_Anambra_State_South_Eastern_Nigeria#fullTextFileContent Vol.4(2) Pages: 52-55
  
  
• Okpogba AN, Ogbodo EC, Amah AK, Chinaka CN, Ujowundu FN, Modo EU, Wopara I, Okpogba JC. (2019) Assessment of rheological indices of chickens (Gallus gallus domestica) exposed to factory sites in Nnewi, Anambra State, South Eastern Nigeria, Indian Journal of Forensic and Community Medicine
  https://www.ijfcm.org/journal-article-file/9479 Vol.6(2) Pages: 96-8
  
  
• Modo, E. U., Orji, B. O., Wopara, I., Agiang, M. A. and Uboh, F. E. (2019) Effect of Uppercott exposure on the liver of female albino wistar rats , FUDMA Journal of Sciences (FJS)
  https://fjs.fudutsinma.edu.ng/index.php/fjs/article/view/1610/1272 Vol.3(3) Pages: 613-620
  
  
• Orji Blessing O., Modo Emmanuel U., Sulyman Abubakar S., Michael Vera E. (2019) Factors Influencing Sudden Infant Death Syndrome (SIDS) In Nigera, South South Journal of Culture and Development
  https://www.researchgate.net/publication/371006753_Factors_influencing_sudden_infant_death_syndrome_SIDS_in_Nigeria Vol.21(2) Pages: 130-149
  
  
• Wopara Iheanyichukwu, Awah M Francis, Modo Emmanuel U, Adejinmi O Ruth. (2018) Evaluation of free radical scavenging capability of Telfairia occidentalis (UGU) and Pterocarpus soyavxii (OHA) ethanolic leaf extracts, International Journal of Chemistry Studies
  https://www.chemistryjournal.in/assets/archives/2018/vol2issue2/2-2-23-458.pdf Vol.2 (2) Pages: 78-81
  
  
• Wopara I, Uwakwe AA, Modo EU, Ikenazor HO, Offor H, Ofodile JO. (2018) Possible effect of Sphenocentrum jollyanum, Baphia nitida and seeds of Pinus koraiensis and sildenafil on sodium, potassium, urea and creatinine levels of albino rats, International Journal of Biology Research
  https://www.researchgate.net/publication/324755127_Impact_Factor_RJIF_522_wwwbiologyjournal#fullTextFileContent Vol.3(2) Pages: 45-50
  
  
• Modo Emmanuel U, Agiang Margaret A, Uboh Friday E, Orji Blessing O, Okoro Favour, Oplekwu Rowland (2018) Uppercott: Implication in nephrotoxicity in male albino wistar rats, International Journal of Biology Research
  https://www.biologyjournal.in/assets/archives/2018/vol3issue2/3-1-87-286.pdf Vol.3(2) Pages: 5-10
  
  
• Wopara I, Awah M. Francis, Modo Emmanuel U. and Ndubueze G. Miracle (2018) Comparative studies on the antioxidant activity of selected alcoholic and non-alcoholic wines commonly consumed in Madonna University, Nigeria , GSC Biological and Pharmaceutical Sciences
  https://gsconlinepress.com/journals/gscbps/content/comparative-studies-antioxidant-activity-selected-alcoholic-and-non-alcoholic-wines-commonly Vol.3(1) Pages: 028–034
  
  
• Etim O. E., Ben I. O., Modo E. U., & Bassey U. E. (2017) Anti-ulceration, anti- diarrheal and anti-enteropooling potential of methanol extract of root of Napoleona imperialis in albino rats, International Journal of Academic Research and Reflection
  https://www.idpublications.org/wp-content/uploads/2017/03/Full-paper-ANTI-ULCERATION-ANTI-DIARRHEAL-AND-ANTI-ENTEROPOOLING-POTENTIAL-OF-METHANOL.pdf Vol.5 (2) Pages: 30-8
  
  
• Modo Emmanuel U., Uboh, Friday E., Agiang, Margaret A., and Ewere, Efosa, G. (2017) Exposure to Uppercott induces hepatotoxicity in male albino wistar rats, International Journal of Scientific World
  https://www.sciencepubco.com/index.php/IJSW/article/view/7442 Vol.5 (1) Pages: 74-79
  
  
• Modo Emmanuel U., Okoro Favour., Orji Blessing., and Njoku Rex-Clovis C. (2017) Zika virus, the way forward: Nigeria as case study, International Journal of Scientific World
  https://www.sciencepubco.com/index.php/IJSW/article/view/7900 Vol.5 (2) Pages: 96-105
  
  
• Modo Emmanuel U, Uboh Friday E, Agiang Margaret A, Orji Blessing, Njoku Rex- Clovis C and Eteng Ofem E. (2017) Exposure to uppercott pesticide induces reproductive toxicity in male and female rats, Journal of Pharmacognosy and Phytochemistry
  https://www.phytojournal.com/archives/2017/vol6issue4/PartS/6-4-214-582.pdf Vol.6 (4) Pages: 1309-1315
  
  
• Modo Emmanuel U., Uboh Friday E., Agiang Margaret A., Dongo Bright S., Etim Gabriel O., Wopara Iheanyichukwu (2017) Exposure to Uppercott affects hematological indices in male albino wistar rats, EUROPEAN JOURNAL OF PHARMACEUTICAL AND MEDICAL RESEARCH (ejpmr)
  https://www.ejpmr.com/home/abstract_id/2840 Vol.4 (9) Pages: 59-64
  
  
• ORJI Blessing O, IGBOKWE Gabriel E, Anagonye Callistus O, Modo Emmanuel U. (2017) Chemical content of the periwinkle shell and its suitability in thin layer chromatography, International Journal of Chemistry Studies
  https://www.chemistryjournal.in/archives/2017/vol1/issue2/1-2-17 Vol.1 (2) Pages: 9-11
  
  
• Ebenezar Idowu O. Ajayi., Emmanuel U. Modo., Adetayo O. Adebamowo., Uttam Chand Benerjee., Olumide O. Tewe., and Olufunso Olabode Olorunsogo (2016) Inhibitory Activity of Ethanol Extract of Manihot esculenta on Mitochondrial Membrane Permeability Transition Pore and Caspase 3 in Type 2 Diabetes Mellitus, International Journal of Biochemistry Research and Review
  https://www.researchgate.net/publication/288829002_Inhibitory_Activity_of_Ethanol_Extract_of_Manihot_esculenta_on_Mitochondrial_Membrane_Permeability_Transition_Pore_and_Caspase_3_in_Type_2_Diabetes_Mellitus Vol.9 (4) Pages: 1-10
  
  
• Modo E., Okwandu N., and Dongo B (2015) Comparative effects of vitamin C and vitamin E pre-treatment in acute paracetamol induced toxicity on the liver of rats, World Journal of Pharmaceutical Sciences
  https://www.researchgate.net/publication/320160995_Comparative_effects_of_vitamin_C_and_vitamin_E_pre-treatment_in_acute_paracetamol_induced_toxicity_on_the_liver_of_rats Vol.3 (3) Pages: 407 - 412
  
  
• Remy U., Etim, O. E., and Modo E. U. (2015) Characterization of Alkaloid and Flavonoid Bioactive Compounds in Methanolic Root Extract of Napoleona imperialis, International Journal of Science and Research
  https://www.researchgate.net/publication/320161083_Characterization_of_Alkaloid_and_Flavonoid_Bioactive_Compounds_in_Methanolic_Root_Extract_of_Napoleona_imperialis Vol.4(1) Pages: 2817-2819
  
  
• Okwandu, N., Ifeme, J., and Modo, E. (2015) Effects of some antihistamines on rat plasma acid phosphatase and lactate dehydrogenase activity, World Journal of Pharmaceutical Research
  https://wjpr.net/abstract_file/2567 Vol.4 (4) Pages: 1650-1658
  
  
• Edet Love Mendie, Etim Okon Effiom and Modo Emmanuel Uchechukwu (2014) In vivo effect of Citrullus Lanatus seeds extract on liver function on acute butylated hydroxytoluene induced oxidative stress in Albino rats, World Journal of Pharmaceutical Sciences
  https://www.researchgate.net/publication/320161230_In_vivo_effect_of_Citrullus_Lanatus_seeds_extract_on_liver_function_on_acute_butylated_hydroxytoluene_induced_oxidative_stress_in_Albino_rats Vol.3 (1) Pages: 133-139